Research and Development (R&D): Discovery and development of new compounds. Understanding the therapeutic value of cannabinoids is essential for implementing future developments for clinical phases.

Production of active ingredients: Synthesis of active pharmaceutical ingredients (API). At this stage, IMP has extensive experience in developing extraction and purification processes for cannabinoids, as well as cultivating cannabis for medical and scientific use.

Formulation: Combining APIs with excipients to create the final form of the drug. This stage includes the intermediates of drug manufacturing that IMP is currently developing.

Packaging: Packaging of the final product for distribution. At this stage, drug stability studies are implemented before reaching the commercial phase.

Quality Control: Ensuring that the product meets regulatory quality and safety standards.

An API is the biologically active substance in a drug. It is the main component that produces the desired therapeutic effect in the patient. In this case, cannabis flowers can be considered an API used for cannabinoid extraction or as a final drug product for direct conditioning for patients (This option is only considered for export outside of Spain).

Quality control is crucial to ensure that medicines are safe and effective. It includes testing and verification at every stage of production to ensure that the final product meets regulatory standards and is free of contaminants and impurities.

IMP Research’s internal quality control includes validated methods for determining primary cannabinoids and related substances, as well as identification and moisture content analysis, following the corresponding monograph.

For other quality control parameters defined by the European Pharmacopoeia, such as pesticides, microbiology, aflatoxins, and heavy metals, IMP Research collaborates with certified GLP laboratories.

Pharmaceutical companies must comply with Good Manufacturing Practices (GMP), which are regulations established by agencies such as the FDA in the United States and the EMA in Europe. These regulations ensure that medicines are consistently and properly manufactured, following appropriate quality standards.

Good Manufacturing Practices (GMP), also known as Normas de Correcta Fabricación (NCF) in Spanish, are a set of guidelines and regulations that ensure medicines are produced consistently and in a controlled manner, meeting the required quality standards for their intended use.

These regulations cover various aspects of pharmaceutical production, including:

1. Pharmaceutical Quality System: Implementation of a quality management system to ensure product integrity and quality.
2. Personnel: Training and qualification of staff involved in manufacturing.
3. Facilities and Equipment: Maintenance of proper facilities and equipment for production.
4. Documentation: Detailed records of all processes and procedures to ensure traceability.
5. Production: Standardized procedures for drug manufacturing and quality control.
6. Quality Control: Testing and verification to ensure products meet specifications.
7. Contracted Activities: Management and oversight of activities performed by third parties.
8. Complaints and Recalls: Procedures for handling complaints and withdrawing defective products from the market.